5 edition of Immunotoxicology of drugs and chemicals found in the catalog.
1986 by Elsevier, Sole distributors for the USA and Canada, Elsevier Science Pub. Co. in Amsterdam, New York, New York, NY .
Written in English
Includes bibliographies and index.
|LC Classifications||RC582.17 .D47 1986|
|The Physical Object|
|Pagination||xvii, 400 p. ;|
|Number of Pages||400|
|LC Control Number||85029330|
Medical definition of immunotoxicology: the study of the effects of toxic substances on the immune system. opmental immunotoxicology, while authors of the other four chapters present and discuss utility of mouse, rat, pig, and nonhuman primate research models for devel-opmental immunotoxicology. Five chapters of the textbook have been devoted to different classes of develop-mental immunotoxicants, including halogenated and polycyclic aromatic hydrocar-. Guidance for industry [electronic resource]: immunotoxicology evaluation of investigational new drugs. Format Online Resource Book Published Rockville, MD: U.S. Dept. of Health and Human Services, Food and Drug Administration, Center for Drug . The immunotoxic effects of drugs are divided into immunosuppression, immunostimulation, hypersensitivity and autoimmunity. The major adverse consequences of immunosuppression are infectious complications and virus-induced malignancies. Flu-like reactions, more frequent autoimmune diseases and hypersensitivity reactions to unrelated Author: Jacques Descotes.
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Read the latest chapters of Immunotoxicology of Drugs and Chemicals: an Experimental and Clinical Approach atElsevier’s leading platform of. Immunotoxicology has been defined as the study of adverse effects on the immune system resulting directly or indirectly from occupational, environmental or therapeutic exposure to chemicals (including drugs), biologic materials and, in certain instances, physiological factors, collectively referred to as agents.
It encompasses studies of altered immunologic events. Immunotoxicology of drugs and chemicals. Amsterdam ; New York: Elsevier, (OCoLC) Online version: Descotes, Jacques, Immunotoxicology of drugs and chemicals. Amsterdam ; New York: Elsevier, (OCoLC) Document Type: Book: All Authors / Contributors: Jacques Descotes.
Immunotoxicology of drugs and chemicals. Amsterdam ; New York: Elsevier ; New York, NY: Sole distributors for the USA and Canada, Elsevier Science Pub.
Co., © (OCoLC) Immunotoxicology (sometimes abbreviated as ITOX) is the study of the toxicity of foreign substances called xenobiotics and their effects on the immune system. Some toxic agents that are known to alter the immune system include: industrial chemicals, heavy metals, agrochemicals, pharmaceuticals, drugs, ultraviolet radiation, air pollutants and some biological materials.
Immunotoxicology of drugs and chemicals by Jacques Descotes, Elsevier Science Publishers, US$ /Dfl (xvii + pages) ISBN 0 1Author: Pierluigi E Bigazzi.
About this book. The human immune system is constantly exposed to chemical contaminants, whether from food, water or air. hot topic that can be directly applied to the prediction and characterization of immunotoxic effects in drugs, chemicals, and environmental contaminants.
where she heads the Laboratory of Immunotoxicology and. Some chemicals that have produced immunologic distur bances in experimental animals and/or humans are listed in Table A detailed overview of drug-induced immune diseases and immunotoxic.
The set of journals have been ranked according to their SJR and divided into four equal groups, four quartiles. Q1 (green) comprises the quarter of the journals with the highest values, Q2 (yellow) the second highest values, Q3 (orange) the third highest values and Q4.
Principles and Methods of Immunotoxicology (LOE $44,; ) and published over journal articles as well as working on many journal editorial boards including: • Biomedical and Environmental Sciences (Academic Press), Editorial Board • Environmental Toxicology (John Wiley & sons), Editorial BoardReviews: 1.
The first comprehensive reference on immunotoxicology using analyses based on molecular effects rather than on animal models. Following an introduction to immune system pathways and toxicity mechanisms from a systemic perspective, the main part of the book surveys individual molecular mechanisms of important immunotoxicants, from PAHs to biopharmaceuticals, and.
Tailored to the needs of scientists developing drugs, chemicals, cosmetics and other products this one-stop reference for medicinal chemists covers all the latest developments in the field of predictive toxicology and its applications in safety assessment. Immunotoxicology Evaluation- authorSTREAM Presentation.
INTRODUCTION: INTRODUCTION This guidance makes recommendations to sponsors of investigational new drugs (INDs) on The Parameters that should be routinely assessed in toxicology studies to determine effects of a drug on immune function, When Additional immunotoxicity studies.
A branch of toxicology that is concerned with identifying the adverse effects of drugs, chemicals or environmental agents on the structure and/or function of the immune system and elucidating the mechanisms responsible for such effects.
Immunotoxicology: Opportunities for Non-animal Test Development Drugs and various chemicals can be classified as immunotoxic compounds. The purpose of this review is. Immunotoxicology, Definition of.
Vohr, Hans-Werner // Encyclopedic Reference of Immunotoxicology;, p A definition of the term "immunotoxicology" is presented.
It refers to a branch of toxicology concerned with identifying the adverse effects of drugs, chemicals or environmental agents on the structure and/or function of the immune system. Immunotoxicology research determines how drugs and environmental chemicals impact the immune system.
Read More. Immunotoxicology DEFINITION Immunotoxicology is a scientific discipline whose aim is to detect, quantify, and interpret direct or indirect alterations of the immune system that occur as a result of exposure to chemicals, pharmaceuticals, recombinant biologicals, or environmental and occupational pollutants.
The second section on immunodiagnostics has been further expanded to describe widely used molecular techniques and is followed by a systematic coverage of drugs affecting the immune system, revised to cover recent developments. The book concludes with a chapter on immunotoxicology.
Immunotoxicology. Humans receive significant ambient daily exposures to multiple environmental contaminants, including by-products of combustion (polycyclic aromatic hydrocarbons) and plastics (phthalates and organotins).
the Schlezinger laboratory investigates how chemicals within the mixtures may interact to enhance deleterious effects. Immunopharmacology and Immunotoxicology ( - current) Formerly known as. Journal of Immunopharmacology ( - ) Browse the list of issues and latest articles from Immunopharmacology and Immunotoxicology.
List of issues Latest articles Partial Access; Volume 42 Volume 41 Volume 40 Molecular Immunotoxicology 1st Edition of this hot topic that can be directly applied to the prediction and characterization of immunotoxic effects in drugs, chemicals, and environmental contaminants.
About the : Hardcover. The human immune system is constantly exposed to chemical contaminants, whether from food, water or air.
Some chemicals directly elicit an immune response, while others indirectly activate or deactivate components within the immune system. Thus when tracking or predicting the effect of a chemical Author: Emanuela Corsini. Immunotoxicology of Drugs and Chemicals. Book by Descotes Jacques.
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Full Description:" Immunotoxicology of Drugs and Chemicals: and Experimental and Clinical Approach adds to the reader's knowledge. Everything you read will fill your head with new information, and you'll never know when it might be useful. The more knowledge you have, the better equipped to solve the problems you have faced.
The goal of the Immunotoxicology and chemical allergy speciality section (ITCASS) is to serve as a focal point for members of EUROTOX interested in immunotoxicology, chemical allergy, drug allergy and food allergy through educational activities that emphasize fundamental development and application in immunotoxicology, chemical allergy, drug.
NIOSHTIC-2 Publications Search. Search NIOSHTIC Advanced Search Search Help About NIOSHTIC-2 Feedback. Immunotoxicology: effects of, and response to, drugs and chemicals.
Authors Dean-JH; House-RV; Luster-MI Source Principles and Methods of. The field of immunotoxicology has undergone considerable growth and expansion since its inception in the early s.
The discipline was founded by combining knowledge from the areas of immunology and toxicology to study the effects that xenobiotics exert on the immune system. It has progressed from. Principles and Methods of Immunotoxicology.
Emphasizing the cornerstones of toxicology-people differ, dose matters, and things change, the book begins with a review of the history of toxicology and followed by an explanation of basic toxicological principles, agents that cause toxicity, target organ toxicity, and toxicological testing.
The book includes many chapters on specific environmental agents, therapeutic drugs, biological agents, and drugs of abuse, as well as on immune-mediated toxicity in specific organ systems.
Category: Medical Immunotoxicology And Immunopharmacology Third Edition. In Immunotoxicity Testing: Methods and Protocols, expert researchers explore these changes, providing the reader with current, lab-ready procedures, along with the corresponding background information that is necessary to identify effective testing approaches for chemicals and drugs.
Among the first volumes to meld consideration of Format: Hardcover. The term immunotoxicity denotes adverse health effects resulting from the various interactions of xenobiotics (i.e. drugs, industrially and environmentally occurring chemicals, or naturally occurring substances) with the immune system.
This book focuses on the role of T-cell subpopulations in the manifestation of immunotoxic : Ernst Gleichmann. The human immune system is constantly exposed to chemical contaminants, whether from food, water or air.
Some chemicals directly elicit an immune response, while others indirectly activate or deactivate components within the immune system. Thus when tracking or predicting the effect of a chemical on the immune system, many different pathways and modes of action need to be.
Molecular Immunotoxicology - Kindle edition by Corsini, Emanuela, Van Loveren, Henk. Download it once and read it on your Kindle device, PC, phones or tablets. Use features like bookmarks, note taking and highlighting while reading Molecular cturer: Wiley-VCH.
Immunotoxicity risk assessment of chemicals is an evaluation of the potential for unintended effects of chemical exposure on the immune system.
These effects manifest as following principal types of immunotoxicity: immunosuppression involving infection and carcinogenesis etc, immunoaccentuation involving sensitization and autoimmunity, or Cited by: 1.
Immunotoxicology: An overview. Concern over the potential toxic effects of chemicals and certain drugs on the immune system prompted the application of these methods to assess the safety evaluation of the immune system and the establishment of the subdiscipline of immunotoxicology within toxicology.
Methods have been selected and optimized Cited by: 1. This report is the product of the Subcommittee on Immunotoxicology, which included clinicians, epidemiologists, toxicologists, pathologists, and biochemists.
Our intent was to consider various kinds of basic research that might reveal markers of environmental exposure and disease, even if the original goal of the research had nothing to do with. Immunotoxicity Testing of Drugs and Chemicals CITT A Comprehensive Immunotoxicity Tier-1 Testing protocol integrated into a days repeated dose toxicity test PARA Bioscience GmbH, Fabrikstr.3, D Gronau, Germany Background: The assessment of immunotoxicity is an important component of safety assessment within preclinical toxicology.
In Immunotoxicity Testing: Methods and Protocols, expert researchers explore these changes, providing the reader with current, lab-ready procedures, along with the corresponding background information that is necessary to identify effective testing approaches for chemicals and : $ Immunotoxicology in veterinary medicine deals mostly with the problems of dominant ecological toxicants, such as pesticides.
Therefore, the veterinary immunotoxicology can be referred to as ecoimmunotoxicology. DNA-recombinant biopreparations and drugs. There are clinical reports of a syndrome which has been described as follows: Chemicals (odorous and nonodorous VOC's, solvents, pesticides, etc.) cause a 'sensitization' (induction phase) in a subset of individuals.
Upon subsequent exposure to lower concentrations, these individuals may respond in.Allergy and Immunotoxicology in Occupational Health is a valuable resource for professionals and researchers in the occupational health sector, who will discover novel insights into immune effects, providing a foundation for future considerations of the health impairments caused by environmental and occupational exposure to these substances.Author of Immunotoxicology of drugs and chemicals, An introduction to immunotoxicology, Handbook of Safety Pharmacology, Alexis Carrel,pionnier de la chirurgie vasculaire et des transplantations d'organes, Les pièges de la chirurgie vasculaire, Principles and Methods of Immunotoxicology, Volume 1, An introduction to immunotoxicology, Drug-induced immune .